Malignant Hyperthermia

Malignant hyperthermia is a severe reaction to certain drugs used for anesthesia. This severe reaction typically includes a dangerously high body temperature, rigid muscles or spasms, a rapid heart rate, and other symptoms. Without prompt treatment, the complications caused by malignant hyperthermia can be fatal.

In most cases, the defective gene that puts you at risk of malignant hyperthermia is inherited, though sometimes it's the result of a random genetic defect. Genetic testing can reveal whether you have an abnormal gene. This genetic disorder is called malignant hyperthermia susceptibility (MHS).

Treatments for malignant hyperthermia include the medication dantrolene (Dantrium, Ryanodex, Revonto), ice packs and other measures to cool body temperature, as well as supportive care.

Education

Due to the serious nature of Malignant Hyperthermia, education is recommended on a periodic basis.  Our PowerPoint presentation focuses on epidemiology, job assignments, and the importance of a timely response.

It can be downloaded, and contains audio to for simple viewing.  The Quiz is to check for competence.  The administrator or DON may request answers by emailing.

Mixing Revonto

Mixing Revonto is an important aspect in treating any Malignant Hyperthermia Crisis.  Time is off the essence, and any delay can result in poor outcomes for patients.

The video shows how to mix quickly mix Dantrolene without compromising aspects to patient care.  (start at 1:02)

(This video will be replaced shortly)

Mixing Ryanodex

The new agent used for Malignant Hyperthermia Crisis in Ryanodex.  The medication is more concentrated, and easier to mix.

The video shows how to mix quickly mix Ryanodex without compromising aspects to patient care.  The mixing procedure starts at the 2:41 mark.

Malignant Hyperthermia Crisis Demo

The following video is a Malignant Hyperthermia Crisis demonstration.  They go over numerous sign and symptoms, medications, and proper procedures.

The video is queued to when the signs and symptoms of MH crisis are first identified. 

(~6 minutes: start at 6:54 mark)

Malignant Hyperthermia Crisis Demo #2

The following video is a 2nd Malignant Hyperthermia Crisis demonstration.  They video is a little more clear than the above video.  

The video is queued to when the signs and symptoms of MH crisis are first identified. 

(~4 minutes - start at 2:23)